Fredo B. a écrit:selon MP
We recommend consuming 1 to 3 grams 30 minutes before your workout as a focus enhancer and cell volumizer or 30 minutes before sleep as a neurotransmitter.
[autoquote d'ailleurs]
Il existe des mises en garde, comme tout supplément à n'utiliser qu'en parfaite connaissance de cause et sous votre responsabilité:
La consommation de taurine n'est pas conseillée pour les enfants, les femmes enceintes ou les malades du foie et/ou des reins. De plus, les personnes souffrant de problèmes cardiaques ou de tension ne doivent pas consommer plus de 2 canettes contenant de la taurine par semaine.
Consommer de l'alcool, des médicaments ou des drogues avec de la taurine peut présenter des risques, car celui-ci accélère l'absorption de ces substances par le corps.
D'après l'avis de l'AFSSA [7], la consommation de deux canettes par jour apporte des doses de taurine et de glucuronolactone environ 10 fois (2000 mg) et mille fois (1200 mg) plus élevées respectivement que les doses journalières apportées par l’alimentation (dépassant rarement 180 mg par jour pour la taurine (Laidlaw et al., 1990) et 1 à 2 mg par jour pour la glucuronolactone).
http://fr.wikipedia.org/wiki/Taurine
Synthèse:
A fortes doses (>3g) peut aider à dormir dans certaines circonstances [edit suite à lecture plus bas post Gromit)
A faibles doses (environ1g ) excitant
Donc à prendre à faible dose avant training et/ou le matin, ou bien 3 à 5g après ou au coucher pour récupérer + rapidement, détoxifier l'organisme et profiter de ses propriétés sur la libération d'oxyde nitrique.
Taurine : à éviter en même temps que la béta alanine, car il y a compétition entre les 2 AA, et ça nuit à leur bonne absorption.
Dans ce cas, Béta alanine : avant training, et taurine : après ou le soir avant dodo (améliore la récup) (soir uniquement certainement mieux, car sinon en post risque d'effet de somnolence si prise >3G)
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Taurine is a conditionally-essential amino acid which is not utilized in protein synthesis, but rather is found free or in simple peptides. Taurine has been shown to be essential in certain aspects of mammalian development, and in vitro studies in various species have demonstrated that low levels of taurine are associated with various pathological lesions, including cardiomyopathy, retinal degeneration, and growth retardation, especially if deficiency occurs during development. Metabolic actions of taurine include: bile acid conjugation, detoxification, membrane stabilization, osmoregulation, and modulation of cellular calcium levels. Clinically, taurine has been used with varying degrees of success in the treatment of a wide variety of conditions, including: cardiovascular diseases, hypercholesterolemia, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, alcoholism, and cystic fibrosis. (Alt Med Rev 1998;3(2):128-136)
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Introduction
Taurine (2-aminoethanesulfonic acid, see Figure 1) is a conditionally-essential amino acid which is not utilized in protein synthesis, but rather is found free or in simple peptides. First discovered as a component of ox bile in 1827, it was not until 1975 that the significance of taurine in human nutrition was identified, when it was discovered that formula-fed, pre-term infants were not able to sustain normal plasma or urinary taurine levels.1 Signs of taurine deficiency have also been detected in children on long-term, total parenteral nutrition,2 and in patients with "blind-loop" syndrome.3 In vivo studies in various species have shown taurine to be essential in certain aspects of mammalian development, and have demonstrated that low levels of taurine are associated with various pathological lesions, including cardiomyopathy, retinal degeneration, and growth retardation, especially if deficiency occurs during development.4
Derived from methionine and cysteine metabolism, taurine is known to play an important role in numerous physiological functions. While conjugation of bile acids is perhaps its best-known function, this accounts for only a small proportion of the total body pool of taurine in humans. Other metabolic actions of taurine include: detoxification, membrane stabilization, osmoregulation, and modulation of cellular calcium levels. Clinically, taurine has been used in the treatment of a wide variety of conditions, including: cardiovascular diseases, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, and cystic fibrosis. An analog of taurine, acamprosate, has been used as a treatment for alcoholism.
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Cardiovascular Effects
Taurine comprises over 50 percent of the total free amino acid pool of the heart.9 It has a positive inotropic action on cardiac tissue,10 and has been shown in some studies to lower blood pressure.11,12 In part, the cardiac effects of taurine are probably due to its ability to protect the heart from the adverse effects of either excessive or inadequate calcium ion (Ca2+) levels.13 The consequence of Ca2+ excess is the accumulation of intracellular calcium, ultimately leading to cellular death. Taurine may both directly and indirectly help regulate intracellular Ca2+ ion levels by modulating the activity of the voltage-dependent Ca2+ channels, and by regulation of Na+ channels. Taurine also acts on many other ion channels and transporters. Therefore, its action can be quite non-specific.14 When an adequate amount of taurine is present, calcium-induced myocardial damage is significantly reduced, perhaps by interaction between taurine and membrane proteins.15 At least one study has suggested taurine's ability to function as a membrane stabilizer is related to its capacity to prevent suppression of membrane-bound NaK ATPase.16
Other research demonstrates taurine can protect the heart from neutrophil-induced reperfusion injury and oxidative stress. Because the respiratory burst activity of neutrophils is also significantly reduced in the presence of taurine, perhaps taurine's protective effect is mediated by its antioxidative properties.17
Azuma and associates have observed that taurine alleviates physical signs and symptoms of congestive heart failure (CHF).18-20 Chazov et al were able to demonstrate that taurine could reverse EKG abnormalities such as S-T segment changes, T-wave inversions, and extra systoles in animals with chemically-induced arrhythmias.21
A double-blind, placebo-controlled crossover study suggested, "taurine is an effective agent for the treatment of heart failure without any adverse effects." 22 Fourteen patients (9 men and 5 women) with CHF were evaluated initially and baseline data were obtained. Patients were assigned a "heart-failure score" based on the degree of dyspnea, pulmonary sounds, signs of right-heart failure, and chest film abnormalities. All patients were continued on digitalis with diuretics and/or vasodilators throughout the study period. Patients received 6 grams per day in divided doses of either taurine or placebo for four weeks, followed by a 2-week "wash-out" period. Prior to the cross-over period, baseline data were obtained for the following study period, in which patients received placebo or taurine, whichever was not taken during the first study period. Heart-failure scores fell from 5.8 ± 0.7 before taurine administration to 3.7 ± 0.5 after taurine (p < 0.001); the score did not change significantly during the placebo period. A "favorable response was observed in 79 percent (11/14 patients) during the taurine-treated period and in 21 percent (3/14 patients) during the placebo-treated period; 4 patients worsened during the placebo period, whereas none did during the taurine period (p less than 0.05)."22
Research has also been conducted in animals to determine whether oral taurine increased survivability in CHF which resulted from surgically-induced aortic regurgitation. Albino rabbits received either taurine (100 mg/kg) or placebo after surgical damage to the aortic cusps, which produced aortic regurgitation. "Cumulative mortality at 8 weeks of non-treated rabbits following aortic regurgitation was 52% (12/23 animals) compared with 11% (1/9 animals) in taurine-treated group (p less than 0.05)... Taurine prevented the rapid progress of congestive heart failure induced artificially by aortic regurgitation, and consequently prolonged the life expectancy." 23
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[Edit]@quote Gromit p1
"- Taurine (entre 3 et 6gr avant ou après l'effort ou au couché): détend le système nerveux, supprime les crampes ou empêche leur apparition, augmente la congestion, protège le coeur lors d'efforts violents. "
Dernière édition par Laurent E. le 30/08/2009 18h11, édité 3 fois.